Monday, 25 August 2014

Japan ready to offer flu drug for Ebola treatment

 Japan said Monday it is ready to provide a Japanese-developed anti-influenza drug as a possible treatment for the rapidly expanding Ebola outbreak.

Chief Cabinet Secretary Yoshihide Suga told reporters that Japan can offer favipiravir, developed by a subsidiary of Fujifilm Holdings Corp., at any time at the request of the World Health Organization.

Suga said Japan is watching for a decision by WHO that would provide more details on the use of untested drugs. In case of an emergency, Japan may respond to individual requests before any further decision by WHO, he said.

WHO said earlier this month that it is ethical to use untested drugs on Ebola patients given the magnitude of the outbreak.

The drug, developed by Fujifilm subsidiary Toyama Chemical Co. under the brand name Avigan to treat new and re-emerging influenza viruses, was approved by Japan's health ministry in March. Fujifilm is in talks with the U.S. Food and Drug Administration on clinical testing of the drug in treating Ebola, company spokesman Takao Aoki said.

The company has enough stock of favipiravir for more than 20,000 patients, Aoki said.

He said Ebola and influenza viruses are the same type and a similar effect can theoretically be expected for Ebola.

Several drugs are being developed for the treatment of Ebola. They are still in the early stages and there is no proven treatment or vaccine for the often fatal disease.

Favipiravir inhibits viral gene replication within infected cells to prevent propagation, while other anti-viral drugs often are designed to inhibit the release of new viral particles to prevent the spread of infection, the company said.

Recently, two American doctors recovered from Ebola after being treated with the experimental drug ZMapp, though it was unclear whether they were cured by the drug.

ZMapp, developed by Mapp Biopharmaceutical Inc., had never been tested on humans, although an early version worked in some Ebola-infected monkeys. It is aimed at boosting the immune system's efforts to fight off Ebola.

Ebola has killed more than 1,400 people in West Africa in the latest outbreak.

Five-year-old demands gun to shoot suspect

Policemen attached to the State Criminal Investigation Department, Yaba, Lagos State were stunned on Friday after a five-year-old girl demanded a gun from the police so that she could shoot the man who sexually defiled her.
The suspect, Okafor, 22, was said to have taken the girl, Chimuanya, into an uncompleted building at Dansa area of Badagry and sexually defiled her.
The minor was with her mother who was a trader when Okafor told her to come.
A police source at the SCID revealed that the suspect took the girl to the building and pulled her down, leaving her with bruises.
The suspect so much penetrated the girl that he left her bleeding and leaping.
Apparently in fear and hurry to return the girl to her mother, he didn’t bother or noticed enough to clean the blood dripping down her legs.
A police inspector disclosed that if the child was given a gun, she would have shot the suspect dead because she meant what she said.
He said the girl bled so much that her parents had to ask her what happened and she opened up.
When the suspect was arrested and taken to the SCID, the girl asked a policewoman to give her a gun so that she would shoot the suspect dead because “he wound me”.

Ibori’s kinsmen back Ndokwa man as Uduaghan’s successor

 Political leaders of the Delta Central Senatorial District have started to soft pedal on power shift to Delta North Senatorial District of the state.
Prior to this development, the race to succeed Governor Emmanuel Uduaghan next year had assumed a battle royale among the three senatorial districts of the state.
The two mouth-piece of the largely populated district – the Urhobo Political Forum and Urhobo Political Congress – at the weekend in a separate remarks expressed preference to support power shift to Anioma ethnic nationality, comprising the Ibo speaking axis of the state.
The pressure groups categorically rejected the choice of an Ika man succeeding Governor Uduaghan next year.
The leadership of the groups, led by the Senior Political Adviser to Governor Uduaghan, Chief Ighoyota Amori, a staunch loyalist of the former Governor James Ibori, and the Commissioner representing Delta State on the board of the Niger Delta Development Commission, Sir Tom Amioku, also Ibori’s man, gave reasons why an Ndokwa man must succeed Uduaghan next year against all odds from Ika axis of Delta North Senatorial District.
In the Ika axis of the state alone, no fewer than five aspirants, including Senator Ifeanyi Okowa; the Chief of Staff to the Governor, Dr. Festus Okubor; former Acting Governor of the state, Hon. Sam Obi; and the Permanent Secretary, Government House, Asaba, Anthony Obuh, have declared interest.
Receiving a Peoples Democratic Party governorship aspirant, Chief Johnson-Ossai-Opone, at Mosogar, Chief Amori said the Urhobos would back Delta North Senatorial District’s ambition if their candidate is from Ndokwa, compsiring Ndokwa/Ukwuani Federal Constituency.
According to him, since Asaba has the state capital, which forms part of the old Benin Province, “it was only fair to concede the 2015 governorship to Ndokwa, which though is part of Delta North, but was originally in the old Delta Province.
“In the interest of equity and fairness, Ndokwa area that produces the bulk of the oil and gas in Delta North Senatorial District should be favoured, at least to give the area a sense of belonging.”
Speaking for UPC, Sir Amioku, who received Ossai-Opone at Egborode Community in Okpe Local Government Area, acknowledged that the Urhobos of Delta Central Senatorial District, were at home with Ndokwa because of several years of convivial relationship through inter-marriage, culture and language in the old Delta Province.
Chief Amioku said the UPC and indeed the Urhobos were encouraged by the quality governorship aspirants emerging from Ndokwa nation, even as he underscored the track records and pedigree of O ssai-Opone.                                                                                                                                  However Ossai-Opone assured Delta Central Senatorial District stakeholders of his capability as a celebrated Chartered Accountant to give Delta State a well structured, sustainable and equitable development.

Sunday, 17 August 2014

Ebola: How US lab dumped infectious monkeys in Liberia

An island, Farmington Island, with over 60 infected chimpanzees, has been been brought to the fore in Liberia following the outbreak of the Ebola Virus Disease.
The island, popularly called Monkey Island, by Liberians, has been in existence for several years.
However, with the outbreak of the EVD, which has monkeys as one of the primary sources of infection, eyes are turning in the direction of the Island.
The EVD has killed over 1,069 persons in its recent outbreak in West Africa.
Greatly affected by this outbreak are Liberia and Sierra Leone.
Nigeria has so far recorded four deaths from the fast spreading EVD.

An island, Farmington Island, with over 60 infected chimpanzees, has been been brought to the fore in Liberia following the outbreak of the Ebola Virus Disease.
The island, popularly called Monkey Island, by Liberians, has been in existence for several years.
However, with the outbreak of the EVD, which has monkeys as one of the primary sources of infection, eyes are turning in the direction of the Island.
The EVD has killed over 1,069 persons in its recent outbreak in West Africa.
Greatly affected by this outbreak are Liberia and Sierra Leone.
Nigeria has so far recorded four deaths from the fast spreading EVD.
According to information provided in a video by a researcher who visited the Island, the monkeys were used for researches and then released into the Island.
Liberians themselves avoid going to the Island.
A 40 minutes drive outside of the town by road and then a boat ride gets a visitor to the Island.
The island is said to be 40 miles from Monrovia, the capital of Liberia.
The chimpanzees are described as “super aggressive” by the presenter.
The chimpanzees were said to have been used for medical researches at the Liberian Institute for Bio-Medical Research, hence it was not strange before the outbreak of the EVD in Liberia so see so many Liberians with monkeys.
The research was said to have been sponsored by the New York Blood Centre.
The chimpanzees, according to the report, were infected with Hepatitis and River Blindness among other diseases.
Betsy Brotman was the Director of the centre, VILAB, which came into existence in 1974.
An article by the New York Times on July 17, 1984, said one in four out of the chimpanzees used in hepatitis research becomes an asymptomatic carrier and as such must stay in captivity.
Yet, there was the need to release them back into the forest so they could live their normal lives again, Brotman said.
The first set of such chimpanzees were released into the Asagny National Park in the Ivory Coast.
According to Brotman, they did humanity a favour and as such should be given their lives back.
The full article on the subject in the New York Times of July 17, 1984 reads:
Robertsville, Liberia: Standing on the bow of the outboard motor boat rocking in the brown water of the Little Bassa river, Betsy Brotman cupped her hands around her mouth and bellowed toward the jungle island. “Char-lie! Char-lie!”
She turned to a passenger in the boat. “Wait till you see Charlie,” she whispered. “He’s fantastic.” She shouted again: “Char-lie! Char- lie!”
For a while it seemed no one was listening. Then, finally, a small, dark, hulking chimpanzee emerged from the dense bush. He lumbered across the beach and waded thigh-deep into the water. Scowling, he raised his right hand and let fly a rock in the direction of the boat. It plopped into the river several inches short of its target.
“That’s Charlie,” Miss Brotman explained. “Didn’t I tell you? Isn’t he fantastic?”
Charlie is one of about 200 chimpanzees in Liberia who have “retired” as research animals in studies of hepatitis viruses, research that now appears to be close to a successful conclusion. He is the dominant chimp on Red Deer Island, a sort of halfway house for a select group of experimental animals that are in the process of being reintroduced to the wild.
“They did human society a favor,” said Miss Brotman, head of Vilab II, a research facility operated by the New York Blood Center in association with the Liberian Institute for Biomedical Research. “It’s our responsibility to try to pay them back by letting them live out their lives in their natural environment.”
Vilab II, a complex of laboratories, staff housing and screened-in chimp bungalows set in the rain forest about 40 miles from Monrovia, is one of several hepatitis research institutes that are attempting the difficult task of returning “retired” chimpanzees to the wild in Africa. It was established 10 years ago, and about 50 chimps were captured to serve as an initial experimental and breeding colony.
Young chimps are excellent models for hepatitis research because they are so genetically close to humans and exhibit the same biochemical changes from the hepatitis viruses, yet they do not contract the clinical disease that makes tests on humans so risky. Miss Brotman emphasized that no experiment performed at Vilab has ever resulted in the death or disablement of a chimp.
But the chimps lose their value as research animals by the time they reach about four years of age. Since a chimp may live for 40 years, that leaves a long retirement.
Some can be put into zoos or used in breeding programs, but for the rest the prospects are bleak. It is expensive to keep an adult chimpanzee in captivity, and chimps that have outlived their research usefulness are often put to death. Until recently they have not been able to be returned to the wild because they never learned survival skills; most were bred in captivity, but some were taken by poachers who killed the mother and sold the baby for $15,000 or more.

1,500 chimps in US laboratories
With that in mind, Miss Brotman and Alfred M. Prince, the New York- based director of the Vilab project, began in 1978 to try to develop a program to return the chimps to the wild.
Though that may sound like a simple and logical idea, only a few laboratories have set up such programs. There are currently as many as 1,500 chimpanzees in American labs, breeding facilities and zoos. Almost all of them will spend their entire lives behind bars.
About one chimp in every four used in hepatitis research becomes an asymptomatic carrier. These must stay in captivity.
Vilab’s rehabilitation program begins by placing groups of about 10 chimps between 5 and 10 years of age on an island downriver from the institute.
On the island, the chimps are provided with some supplementary food and their progress is carefully monitored. Any animals that are not adjusting to freedom – for example, those that are not eating or are being frequently beaten up by other animals – can be returned to the protection of civilization.
Most of the chimps, however, do appear to gradually become accustomed to life in a natural habitat, Miss Brotman said. They learn to forage for food, build nests in the trees, have sexual relations, give birth – in the last two and a half years four babies have been born on Red Deer Island – care for the young and form a closely knit troop with a normal social hierarchy.
“Many of these animals lived in my house and slept in my bed as infants,” Miss Brotman said. But after they have been two to three years on the island, she added, “even I can’t walk among them safely. An adult male chimp weighs in at about 150 pounds, is stronger than a man and far more aggressive than a gorilla.”

Life without groceries
The process does not end there, however. After five or six years on the island, the chimps need to be transferred to a game reserve where they will have enough space, roughly one acre per chimp, to fend for themselves without anyone bringing them groceries. The area into which they are released must also not have other chimpanzee troops too close by, since that could lead to conflicts that the tenderfoot chimps, unused to the laws of the jungle, would probably lose.
A first group of 10 chimpanzees is scheduled to be released this summer in the Asagny National Park in the Ivory Coast, one of only a handful of reserves in West Africa that conservationists consider reasonably well- protected from poachers and other forms of human encroachment.
For their first year or so in the wild, the chimps will wear radio telemeters on collars, each with its own frequency, so that every individual’s whereabouts and progress can be monitored. Within two years, the collars will disintegrate.
While there is no guarantee that everything will work out as planned, there are encouraging signs, such as Charlie throwing the rock at Miss Brotman, an aggressive display that suggests that Charlie has become a true troop leader and is no longer anyone’s pet.
“The point is to give them a quality of life they couldn’t have in even the best facility,” Miss Brotman said. ”It’s only right. They really are near human, you know.”

Wednesday, 13 August 2014

Breaking News: Ebola: 21 quarantined in Enugu

Another set of 21 Nigerians suspected to have been infected with the deadly Ebola virus have been quarantined in Enugu, Enugu State, the Minister of Information, Labaran Maku, has confirmed.
Briefing State House correspondents after the weekly Federal Executive Council meeting presided over by President Goodluck Jonathan on Wednesday, Maku blamed the development on a nurse who defiled medical directives and travelled from Lagos to Enugu.
Consequently, all the 21 people had to be quarantined since they have secondary contact with the Liberian, Patrick Sawyer, who imported the deadly virus into Lagos, Nigeria.
The Minister noted that Federal Government had begun sensitization of Nigerians long before the index case was recorded.
He, therefore, advised Nigerians and warned those who have contacts with the victim to obey government’s directives to limit their movements so as to reduce the spread of the disease.
According to Maku, the measures put in place by government to curb the spread of the virus have passed the test of the international organisations operating in the country, including the American International Agencies for Disease Control, the World Health Organization, the United Nations International Children’s Emergency Fund, UNICEF and other relevant bodies.
Maku said: “The international organizations have no need to panic as government is making strong efforts to bring the situation under control.
“The measures we have put in place show professionalism and confidence to ensure that this virus does not spread beyond where it is today.
“Even the World Health Organization has expressed satisfaction with the measures that we have put in place so far, so there should be no need for any anxiety over the existence of the virus in Nigeria.
“There is a strong team in place that has been working and tracing the secondary cases.
“So far, a total of 198 persons have been isolated, with 177 in Lagos alone and 21 persons in Enugu State, that have been quarantined.
“Part of measures being put in place is collaboration with transport owners and operators to prevent the transmission of the virus through the nation’s land borders while protective materials are being provided.”

Tuesday, 12 August 2014

Northern elders to Jonathan: Free our girls or forget 2015

The Northern Elders Forum has asked President Goodluck Jonathan to end insurgency in the North and ensure release of the Chibok girls latest by October ending or forget Northern support in 2015.
In a statement issued in Kaduna on Monday, the Forum posited that the twin demands remain the only conditions by which the President could enjoy Northern backing if he decides to run in 2015.
The statement, signed by Solomon Dalung and Dr. Hakeem Baba-Ahmed, lamented the increasing wave of insecurity, expressing reservation that it poses serious threat to the survival of the nation as well as the conduct of credible elections in 2015.
The statement reads: “The circumstance under which our fellow citizens in and around Gwoza in Borno state in particular live and die will not be tolerated by any people who have a government and a leader sworn to defend them, and they must be reversed immediately.
“In the light of our firm conviction that the insurgency and related security challenges pose threats to the 2015 elections and the survival of our nation, we strongly advise President Goodluck Ebele Jonathan to bring an end to the insurgency in all its manifestations and produce the Chibok girls before the end of October 2014,”
“In the event that President Jonathan fails to do this, Nigerians will be left with the only conclusion that he has forfeited his right to ask for our mandate beyond 2015.
“It is no secret that the vast majority of northerners lament their marginalization, insecurity and poverty, and blame it in large part on the inability or unwillingness of its past and present leaders to utilize all access to power which they enjoyed to bring us redress and relief.
“The NEF joins millions of northerners in appealing to these leaders, General Yakubu Gowon, Alhaji Shehu Shagari, General Muhammed Buhari, General Ibrahim Badamosi Babangida, General Abdulsalam Abubakar, Alhaji Atiku Abubakar and Nnamadi Sambo and all retired Chief Justice of Nigeria from the north to raise their level of involvement in (the) fortunes of our region.
“If these leaders cannot visibly help to transform the fortunes of the north in the next few months, they will live northerners with the damaging impression that they have abandoned the region and the people to its seemingly irreversible decline and ultimate destruction.”
About four months ago, the insurgents, Boko Haram, about 300 school girls from Chibok, Borno State.
Despite international condemnation that greeted the abduction and promises by World leaders, the girls are still in captivity.

Monday, 11 August 2014

Suspected Ebola virus victim discovered in Lagos estate

A suspected Ebola virus victim has been discovered in the Lagos State Property Development Corporation estate in Isheri area of Lagos State.
The estate shares a close boundary with Ogun State in the Isheri area.
The man, identified to be from Niger Republic, was dropped on Saturday by the gate of the estate by a commercial motorcyclist, popularly called okada, who sped off after doing so.
The man, who could no longer talk, had blood all over his nose and mouth, without signs of having been beaten.
He was coughing out blood.
The residents of the estate immediately raised the alarm, suspecting Ebola.
This was more so as the okada man who brought him sped off.
The residents of the estate immediately put a call through to the Lagos State Emergency Management Service and the federal authorities for help.
It took several hours before the man was picked up by the health authorities.
The residents, sequel to the development, have resolved to avoid taking commercial motorcycles until the case is proven not to be Ebola.
The fear is that if it is a case of Ebola, the likelihood of the okada man having become infected could not be ruled out.
The estate residents called a meeting where the resolutions were taken.